Existem diversos tipos diferentes de células gigante multinucleadas visíveis durante
avaliação microscópica, sendo importante ao médico patologista reconhecer e saber
relacionar este achado com o provável diagnóstico do paciente. Monócitos/macrófagos são células imunes inatas com diversas funções que vão desde a fagocitose de
microorganismos até a formação de uma ponte com o sistema imune adaptativo. Um
atributo menos conhecido dos macrófagos é sua capacidade de se fundirem para formar
células gigantes multinucleadas. Com base em sua morfologia e funcionalidade, existem
tipos de células gigantes multinucleadas, incluindo: osteoclastos, touton, células gigantes de corpo estranho e células gigantes de Langhans. Ainda, há formação dessas células com origens diferenciadas como de células dendríticas foliculares ou ainda relacionada a
processos neoplásicos. Aprenda mais sobre células gigantes e suas características no nosso post de hoje!
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